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 Wysłany: Czw 14:41, 03 Mar 2011 Temat postu: scarpe nike 2011 Hirschsprung's disease in patient |
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Hirschsprung's disease in patients with human cytomegalovirus UL139 gene polymorphism
Study fewer cases, but it also can not rule out HCMVUL139 gene polymorphisms and the infection of HCMV disease categories. Qi Ying sequencing methods such as the use l9 a low passage HCMV infection isolates were divided into 3 groups 4 genotypes. In their study,[link widoczny dla zalogowanych], the G2b missing gene in this experiment. Considered due to: (1) HCMV during subculture in the cell causing gene mutation; (2) small number of samples; (3) HCMV infection of the disease categories. The results were similar with HCMVUL144 genes, the present study, children with different specimens of the same HD source UL139 nucleotide sequence completely identical, suggesting that the HCMVDNA urine specimens can indirectly reflect the sequence of HCMV infection in the case of end organ. 2 cases of HD patients also collected urine samples (U298, U299) and the intestinal tissue segment spasm, but repeated PCR amplification of intestinal tissue,[link widoczny dla zalogowanych], UL139 genes are negative results, suggesting that the HCMV-specific antigen in the body caused by cellular immune responses No response has led to the formation of ganglion cells in intestines. 24 cases confirmed by surgery in different clinical isolates of clinical type HD dispersed in all UL139 genotypes, indicating that ganglion cells in HD patients without bowel length has nothing to do with the UL139 genotyping. In this study,[link widoczny dla zalogowanych], 24 clinical isolates also completed the sequencing of genes UL139 and UL144,[link widoczny dla zalogowanych], UL139 and UL144 results show no correlation. That the pathogenicity of HCMV, is probably the combined effect of multiple genes decision. HCMV infection and the current relationship between the HD is not clear, on the other HD patients HCMVUL139 gene polymorphism is only the first step in the pathogenicity of HCMV,[link widoczny dla zalogowanych], HCMV only fully understand the biological characteristics of each gene in order to fully revealed in the HCMV infection in the pathogenesis of HD. 4
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