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Hypercapnia significantly sub-analysis of 58 cases


Key words arterial blood gas analysis 【Abstract】 Objective chronic obstructive pulmonary disease in patients with significant hypercapnia tolerance and clinical significance. Methods PaCO2 was significantly higher (> 75mmHg) in 58 patients times to have the brain symptoms of 28 cases as the observation group, 30 patients without symptoms of the brain plays as a control group. Comparison of the two groups. The results of the symptom of the brain and reduce the level of pH value, PaO2 decreased and PaCO2 increased level of speed, but not with the level of PaCO2 values ​​have no direct relationship. Conclusions can be well tolerated in patients with slowly rising significantly hypercapnia. Chinese papers League finishing. Key words arterial blood gas analysis ; hypercapnia; pulmonary clinical encephalopathy often see a high PaCO2, but conscious, there is no brain symptoms appears. To investigate the chronic obstructive pulmonary disease (COPD) patients were significantly tolerated hypercapnia, I select the last 3 years , 27 patients had a significantly higher in patients with hypercapnia, the results of their blood and clinical characteristics of the control analysis are as follows. 1 Materials and methods 1.1 General Information The group of 27 patients, 17 males and 10 females; age of 58 to 87 years old, average 65.6 years old. Course of 6 to 50 years, an average of 12 years. COPD 18 cases of bronchiectasis secondary infection in 5 cases, 1 case of severe hypothyroidism, idiopathic pulmonary fibrosis in 3 cases. Acute onset time 1 ~ 8 days. Symptoms of pulmonary encephalopathy has nothing to do with the length of hospital stay, 14 patients hospitalized because of pulmonary encephalopathy, 6 patients in the hospital, pulmonary encephalopathy symptoms. 7 cases have been sober mind. All patients were given oxygen, anti-inflammatory, antispasmodic and anti-asthmatic cough and other treatment, the condition of patients given respiratory stimulants, corticosteroids,[link widoczny dla zalogowanych], correct acid-base balance and electrolyte disturbances. 8 patients treated with a breathing machine. 5 died, 22 were improved and discharged. 1.2 Methods 27 patients 82 blood gas analysis Charles, choose PaCO2> 75mmHg total of 58 times; the remaining 24 is not selected even if the brain symptoms. In 58 cases times out of 28 cases of brain symptoms appear. In this paper, there are 28 cases of brain symptoms as the observation group and 30 episodes without symptoms of the brain as the control group, the two groups were compared blood gas analysis, two sets of data compared with the t test. 2 results selected pulmonary encephalopathy conscious observation group and control group, both PaCO2> 75mmHg, PaCO2 can reach the highest 120mmHg , blood pH value of the two groups and PaO2 were lower than the observation group lower. Blood HCO-3 in both groups were higher in the control group increased more significantly (P <0.01), Table 1. Table 1, significant hypercapnia compared two groups of blood gas analysis (omitted) 3 Discussion study found that in COPD patients with chronic respiratory failure, brain the occurrence of symptoms in the rising level of PaCO2 not parallel, if prevention of hypoxia, hypercapnia significantly can be tolerated [1]. Our data show that 58 cases of abnormally high meeting PaCO2 (> 75mmHg), only 28 cases had symptoms of pulmonary encephalopathy, in a delirious state. Another 30 conscious, the two groups was no difference in blood PaCO2 values ​​that contrast with the PaCO2 increased conscious or not, no obvious correlation.