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Development of pharmaceutical tablets gasketed


Mouth, because of its moisture barrier properties of materials is far better than the front, so directly through the liner and measures by the side of the porous pad of the vertical section and then through the composite layer interface, the more moisture into the bottle, which will The best wet pad across the village level is very important toward the bottle. (-), Expand the test in the series of laboratory tests of the base number of small vapor permeability (g / m) moisture content (grams per 50 ml bottle at) SB0082952880.0107SB00731.08500.0113SB00428445400103Sg00627.1649f0. 0099SB0012466310. O089 Patchouli righteousness as the experimental drugs pills and surgery t to SFFO132 wax plug, the inner cover packaging polyethylene comparison test results are listed in Table 4. Table 4 shows the village in the fixed pad and process conditions, the humidity and moisture absorption through the bottle contents with the increase or decrease the intensity of moisture. Covered with a polyethylene moisture into the sealed bottle is much larger than the bottle sealed with a liner into the moisture content, and thus replaced with a polyethylene liner Portugal bottle cap closure is feasible. 2. Production test pilot on the basis of the expansion, we are part of the expanded use of optimization out of the pad test, three plants in the Southwest Pharmaceutical, Chongqing pharmaceutical seven plant mass production test market sales of products in addition to collection of user opinions, The other samples from accelerated testing,[link widoczny dla zalogowanych], testing required through the humidity, moisture content and the observed color change drugs, choose to meet the requirements of the pharmaceutical tablet gasket and process conditions, to provide the basis for the use in production. Conclusion The process of development, the Southwest Pharmaceutical three plants, seven pharmaceutical factory in Chongqing,[link widoczny dla zalogowanych], Chongqing Tong Junge pharmaceutical companies, pharmaceutical companies in Chongqing, several trial tests, to provide expert opinion the trial, praised the village were closed bottle better than the cork mat. Southwest pharmaceutical packaging plant fruit three-dimensional C3000 ignorant of more than bottles, the China Chemical Industry Import & Export Corporation company put on the Malaysian market in Chongqing, Xiamen reflect good customer, access to test market a successful track inspection pad = Chongqing pharmaceutical JI 『closed beta loquat syrup, V. ignorant of the sub-syrup, five years continues to meet medical requirements. Visit the village close track pad Andrographis sugar coated pharmaceutical Chongqing Sijun Court, after 6 years as China continues to meet the standard packaging 』1995 Volume 5 3 51 Table 4 Number of drug names juveniles through the humidity (g / m) moisture content (g / day 50 ml bottle) SFFU13-2 Andrographis sugar coated 1.9949O · 0007 Andrographis sugar coated cork sealing wax 25465O. 0009SFF0l3_2 = methyl silicone oil sugar coated 2.9234O. 001l dimethyl silicone sealing wax cork sugar coated pills 3.35430.0012SFFOl3-2 Huoxiang upright 15.4718O. 01356 visits within the cover of ethylene pill lO1.23330.0367 Huoxiang seek righteousness. With liner SFFO31, SFFO13-5, SFFO27-2, SFPO13-2 and cL002 closed mouth, closed mouth bottle, to replace the current widely used as a tablet bottle sealed cork, plastic plug. Experiments show. Composite liner, sealed plastic bottle mouth closed technology is feasible ways to reform the bottle mouth sealed to achieve modernization of the pharmaceutical industry provides a useful packaging conditions. Liner developed non-toxic, stable sealing performance, high efficiency and reasonable price, sources of material wealth; for the closure of the bottle easy to open bottles and re-tighten the seal can be maintained to meet user needs; and cork wax dipped compared Village pad materials dumped less, simplify packaging operations, reduce process wax process, to improve efficiency,[link widoczny dla zalogowanych], saving labor, there are certain economic benefits through the hub tests, we believe that through the temperature to reach a very small addition to the body should have the root mat village good barrier,[link widoczny dla zalogowanych], but can take some measures to improve the sealing efficiency. Such as the mouth of the bottle, caps should be formed, the standard he; plus enhanced sealing plastic seal; separated from the composite layer liner toward the moist layer of the best bottle and so on. Through experiments, we consider that the use liner sealed bottle, the bottle is nothing more than the external moisture entering through three ways: (1) directly through the liner into the bottle; (2) vertical section through the liner into the village edge pity pad of repeated, and then penetrate into the bottle through the composite layer; (3) The contact between the surface layer and the bottle loose, from the formation of micro-gap penetration into the bottle so the bottle's secret Austin,[link widoczny dla zalogowanych], the first choice drug-free village pad. Second, not only required to have some flexibility in liner. To compensate for defects in the mouth of the bottle or the cap impact. But more importantly, seal the bottle after pressing a tight barrier, so that the sealing gasket can play a full role in 52I995Vo1.5No. 3CIIlNAPACILAGING

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