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Shortness of Helicobacter pylori CagA antibodies and gastric dysplasia relationship between membrane


Its mechanism. Branch and the method of sealing one of the object selected in the Second Hospital of Xi'an Jiaotong University, August 1998 ~ April 1999 back to hospital and outpatient endoscopy and Hp 1l8 One check, of which 94 eligible poured into this research, patient can be classified according to three groups: ① 47 cases of liver cirrhosis with portal hypertension group, 35 men down, down 12 females, aged 17 to 76 years, mean (52.3 ± 13.4) years. Are liver cirrhosis, in which hepatitis B (HBV) cirrhosis 37 down,[link widoczny dla zalogowanych], hepatitis C (HCV) cirrhosis of the liver after 8 down, hepatitis B and hepatitis C cirrhosis 2 rounded down. 5 down the line endoscopy examination of patients underwent surgery after One. Pathologically diagnosed as liver cirrhosis, portal pressure measured in patients with portal hypertension confirmed; others were clinical, laboratory tests, abdominal B-and / or CT examination One diagnosis. Liver function by Child-Pugh classification Chong, of which A-l4 cases. B grade 18 down. C-15 cases. ② chronic gastritis; 26 down, down male i5, female l1 down, age 24--68 years, mean (478 ± 148) years old. All patients in this group by endoscopy and histology common diagnosis, and exclusion of lesions of the liver and other systems. @ Functional dyspepsia (FD): 21 patients, 12 males. Female 9 down, aged 29 to 61 years, mean (49.0 ± 10.9) years. This group of patients with only abdominal discomfort, nausea and other symptoms, endoscopy and histological examination but no obvious abnormalities, and exclusion of lesions of the liver and other systems. These three groups of patients were living in Xi'an, in age, gender difference was not statistically significant (P> 005). Excluded are taking non-steroidal drugs, endoscopy within 1 month before the received bismuth and / or antibiotic treatment of patients comparable. Diagnostic criteria; (1) portal hypertension: in patients with liver cirrhosis, with reference to Bayraktar, etc ... standard, both of the following two or more diagnosed as portal hypertension; ① splenomegaly (B super-major axis under the spleen than 13cm); ② platelet count less than 100 × 10 and the values of several white blood cell count of less than 4.0 × 10 'a few (in respect of 3 consecutive units: 710068 Xi'an, Shaanxi Provincial People's Hospital Stem II Section (He Xiaoqin, Shi Liping); Xi'an Jiaotong University Medical ■ Hospital attached to shoot the second hospital of Internal Medicine (Tung Meng) on); @ B over the next portal or splenic vein width of more than 14mm width of more than 10ram; ④ endoscopic esophageal varices; ⑤ of ascites or the endoscopic gastric vein varicose. (2) PHG: endoscopic diagnosis within the main reference Mdc0 diagnostic criteria which ack1】; mild; ① Huan small red spots or scarlet fever-like rash; @ mucosal folds like the surface of red cord; ③ mosaic - white-yellow powder or fine mesh structure of the red background mucosal edema test strider partitioned into a red snake-like; heavy: ① cherry red spots scattered; ② diffuse bleeding gastric lesions. (3) Hp infection: rapid urease test for the same time, Hp Ronin piperazine methyl green stain and a serum Hp-IgG antibody test, using the Second National Symposium Hp positive development of research diagnostic criteria, H]: that there are two or three or more positive H-positive diagnosis, three were diagnosed as negative Hp-negative, and the remaining patients do not access to the Experimental Study of Hp infection. Second,[link widoczny dla zalogowanych], the experimental method a biopsy derived; anterior wall in the antrum during endoscopy from H. 2 - 4em gastric forceps at 2 - 3 blocks, clean the biopsy forceps, the anterior wall of the gastric body (if any lesions in the disease prominent place) gastric forceps 2 to 3 blocks. 2. Rapid urease test yeast; antrum and gastric body tissue of the one,[link widoczny dla zalogowanych], for rapid urease test, respectively. Operating according to instructions. Results Pán off: 5min in a red color as positive. Those who do not change color negative. 3. Histopathology; antrum and gastric body of the 1 ~ 2,[link widoczny dla zalogowanych], conventional biopsy, surgery, respectively, for the Soviet Union Seiichi eosin and methyl green + piperazine Ronin staining (result determination; nuclei showed blue-violet, Hp showed purple red). 4. Serum Hp-IgG antibodies; gastroscopy or second day of the fasting day, pumping blood 2ml,[link widoczny dla zalogowanych], to 3500r/rain centrifuge 15min, discard the sediment, in the 20'U: serum low-temperature refrigerator to be guillotine. H-IgG antibodies by enzyme-linked immunosorbent assay. Hp-IgG antibodies by the quantitative assay kit from Shanghai Biological Technology Co., Ltd. to provide crystal clear, all operations are conducted in strict accordance with the instructions. Third, the statistical approach to using SPSS software, compared with the rate test, correlation test with the level of correlation.
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